In this issue of Disaster Health

Context: All-hazards. Global applications of evidence-based guidance for disaster behavioral health support in disasters. This Commentary introduces trauma signature (TSIG) analysis as an evidence-based method that examines the interrelationship between population exposure to a disaster, extreme event, or complex emergency; and the interrelated physical and psychological consequences; for the purpose of providing timely, actionable guidance for effective mental health and psychosocial support that is organically tailored and targeted to the defining features of the event. At this juncture in the ongoing development of TSIG, we are about to embark on a Delphi process to infuse expert consensus. The overarching goal is to create a fully operational system to provide timely guidance for adapting disaster behavioral health support to the salient psychological risk factors in each disaster. A growing series of TSIG case studies has been published since 2011 and Disaster Health intends to expedite and feature novel TSIG research focusing on late-breaking disaster events.